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They are part of the case built by medical researchers here and the world over for the past three decades, a case that is scientifically conclusive, and the verdict is clear: Smoking is the leading preventable cause of disease and death in this country. But by the late-1980s, the facts were still not enough to deter a new breed of abrasive radio and TV talk show hosts from stoking resentment over the abrogation of Americans freedom to smoke